FSH + IBMX further reduced testosterone-mediated ERK phosphorylation. FSH, aswell as inhibitors of ERK and Src kinase activity, decreased germ cell connection to Sertoli cells in tradition. Using pathway-specific androgen receptor mutants we discovered that the non-classical pathway is necessary for testosterone-mediated raises in germ cell connection to Sertoli cells. Research of seminiferous tubule explants … Continue reading FSH + IBMX further reduced testosterone-mediated ERK phosphorylation